Betulin 1, lup-20(29)-ene-3β,28-diol, also known as betulinol, betuline and betulinic alcohol (Fig. 1), is a pentacyclic triterpene alcohol with a lupane skeleton. Common structural features of the lupane skeleton are its five-membered ring E.To date, it has been reported that betulin, a pentacyclic triterpenoid present in the bark of white birch, has anti-cancer, antibacterial, antifungal, and antiviral activity. Betulin and birch bark extract are already used as food additives. Betulin has also been proposed for the treatment of viral hepatitis and HIV infections. In addition, inhibition of the herpes virus and Epstein-Barr virus with betulin and its derivatives has been reported.
As a result of its wide application in industry and medicine, an urgent problem is its quantitative determination. Along with instrumental methods such as spectrometric and chromatographic methods, the purpose of this study was to evaluate the possibility of voltammetric determination of betulin in substances.
As a result of research, the electrochemical activity of triterpene on carbon-containing electrodes was established, the main parameters of the voltammetric determination were developed, the possibility of quantitative determination of betulin in substances was shown, and the correctness of the results obtained was verified by the method of additives.
|Affiliation of speaker||Tomsk Polytechnic University|
|Position of speaker||аспирант|
|Publication||Journal of Cleaner Production|